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Metallosis: One danger of DePuy hip implant failure

On Behalf of | Feb 9, 2011 | Drug & Medical Device Injuries |

If you are experiencing pain or suffering from a defective medical device,  it’s wise to consult an attorney. For answers about legal issues in this article or with your own malfunctioning medical product, call me directly for help – Lawrence Egerton, 336-273-0508, or e-mail me at [email protected].


One of the complications that patients with a defective DePuy Orthopaedics hip implant may face is metallosis, a condition in which metal particles build up in the tissue around the implanted joint. Thousands of patients with these recalled implants will require revision surgery to replace the device.

Symptoms of metallosis include:

• Pain around the hip joint

• Difficulty walking

• Swelling around the implant area

• Rash that is a sign of dying tissue

Those symptoms may indicate these severe problems:

• Loosening, when the implant does not stay attached to the bone in the right position.

• Fracture, where the bone around the implant may have broken.

• Dislocation, where the two parts of the implant that move against each other are no longer aligned. This happens because tissue around the joint becomes inflamed and weakened, and can’t hold it in place.

• Damage to the nerves, tissues and muscles near the implant area

Background of the hip recall

The hip implants in question are as the ASR XL Acetabular System and DePuy ASR Hip Resurfacing System. In August 2010, the DePuy Orthopaedics company, a subsidiary of Johnson & Johnson, issued a voluntary recall of two hip replacement systems. DePuy stated that “13 percent of patients (1 in 8) who had received the ASR total hip replacement needed to have a revision surgery.”

How metallosis develops

As the ball and the socket of the implant rub against each other, friction scrapes off microscopic ions of cobalt and chromium, which enter the lubricating fluid that surrounds joints. These particles disperse and accumulate in nearby parts of the body, and also flow through the bloodstream.

The immune system reacts to the metal ions by automatically inflaming the area around the debris. The inflammation is the body’s attempt to contain the foreign particles in the inflamed area so the metal can’t spread to the rest of the body.

How metallosis affects the body

Along with the symptoms listed above, there are other problems associated with metallosis.

During revision surgery, doctors often find dense black staining of the synovial membrane  and surrounding muscles. The membrane is a sac filled with fluid that helps certain joints move freely. In the case of the DePuy hip implant, it appears that the immune system inflames cells in  the synovial membrane, causing synovitis. Synovitis is painful, since the inflammation prevents the joint from rotating properly.

Surgeons also often find pseudotumors, masses of inflamed cells that look like tumors. They can be either solid or fluid-filled and have been found more commonly in women and persons of small stature. Patients who had pseudotumors usually had gradually increasing pain.

Doctors have also found greatly elevated levels of cobalt and chromium in hip revision patients. Both metals have been linked to cancer, and cobalt poisoning (cobaltism) has serious side effects including neurological (brain) damage, heart irregularities, and seizures.

The dangers posed by the DePuy hip implant failure become ever more disturbing as time goes by. DePuy has offered to cover “reasonable and customary costs of testing and treatment, including revision surgery,” and to reimburse patients for “reasonable out-of-pocket expenses.”

Obviously the damage that can potentially be caused by one of these defective devices is far greater than that. The severity of the health issues involved and DePuy’s limited offer of compensation mean you need the counsel of an expert hip-replacement attorney. The attorneys at Egerton Law can help.

Media links:

New York Times:

Early Warning

Broken system

More information from Egerton Law:

Documents requesting access to your medical records (Which you should not sign.)

Why you must retain possession of your hip joint (explant) after surgery.

The story of a lost explant.

Has your life been disrupted by problems with a malfunctioning medical product? Do you or someone you know need the advice of a lawyer specializing in defective medical devices? You can get help at the Egerton Law website. The Egerton Law firm and its personal injury attorneys want to help you. Call us at 336-273-0508. E-mail us at [email protected]

Facts about the Egerton Law firm:

• We have built a tradition of helping injured people and their families since the firm was established in 1956.

•We have handled cases in North Carolina, South Carolina, Texas, New York, the District of Columbia, the North Carolina Supreme Court, and U.S. District Court. We have fought cases all the way to the United States Supreme Court.

•Our team of lawyers are dedicated to fighting insurance companies and corporate giants that seek to increase their bottom line at the expense of injured people.

Are you being:

•Pressured to agree to reimbursement for “reasonable” or “out-of-pocket” medical expenses?

•Pressured to sign document you don’t understand? (Don’t sign anything without consulting us.)

•Told to submit bills for medical services to your insurance company or Medicare, and you will be reimbursed later?

Take action and help us to help you. Call or email: 336-273-0508[email protected]. We can advise you on whether you have a case and the process for getting medical care. You will always speak to an attorney on your first call.